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The effect of desflurane on postoperative olfactory memory

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dc.contributor.author Yildiz, I.
dc.contributor.author Bayir, H.
dc.contributor.author Saglam, I.
dc.contributor.author Sereflican, M.
dc.contributor.author Bilgi, M.
dc.contributor.author Yurttas, V.
dc.contributor.author Demirhan, A.
dc.date.accessioned 2019-08-16T13:06:50Z
dc.date.available 2019-08-16T13:06:50Z
dc.date.issued 2016
dc.identifier.issn 1128-3602
dc.identifier.uri https://hdl.handle.net/11499/9854
dc.description.abstract OBJECTIVE: In this study, we investigated the effects of desflurane 6%, on olfactory memory. PATIENTS AND METHODS: This is a prospective clinical study performed with 40 patients aged 18-60 who had elective surgery and American Society of Anesthesiologists (ASA) physical status I-III. The Brief Smell Identification Test (BSIT) was used for evaluating patients' olfactory memories before and after the surgery. Patients received standard general anesthesia protocol and routine monitoring. For induction, 1.5 mg/kg of fentanyl, 2 mg/kg of propofol, and 0.5 mg/kg of rocuronium bromide were administered. Anesthesia was maintained with the inhalational of anesthetic desflurane (6%). The scores are recorded 30 minutes before the surgery and when the Aldrete Recovery Score reached 10 in the postoperative period. Preoperative and postoperative results were compared and p-values <0.05 were considered statistically significant. RESULTS: The patients' mean age was 41.1±12.0. Preoperative total correct answer rate to odorous substances was 92.7%, and postoperative rate was 92.1%. Percentage of the odor substance identification by the patients revealed no statistically significant difference when pre and post-operative rates have been compared (p-value >0.05). CONCLUSIONS: We have observed for the first time in the literature that general anesthesia using desflurane (6%) did not affect short-Term olfactory memory. Further studies will be necessary to confirm our findings with larger sample size. en_US
dc.language.iso en en_US
dc.publisher Verduci Editore en_US
dc.relation.ispartof European Review for Medical and Pharmacological Sciences en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Anaesthetics volatile en_US
dc.subject Desflurane en_US
dc.subject Olfactory memory en_US
dc.subject Smell en_US
dc.subject desflurane en_US
dc.subject fentanyl en_US
dc.subject propofol en_US
dc.subject rocuronium en_US
dc.subject inhalation anesthetic agent en_US
dc.subject isoflurane en_US
dc.subject adult en_US
dc.subject Aldrete Recovery Score en_US
dc.subject anesthesia induction en_US
dc.subject anesthetic recovery en_US
dc.subject Brief Smell Identification Test en_US
dc.subject clinical article en_US
dc.subject clinical trial en_US
dc.subject drug effect en_US
dc.subject elective surgery en_US
dc.subject female en_US
dc.subject functional status assessment en_US
dc.subject general anesthesia en_US
dc.subject health status en_US
dc.subject heart rate en_US
dc.subject human en_US
dc.subject male en_US
dc.subject mean arterial pressure en_US
dc.subject memory assessment en_US
dc.subject odor en_US
dc.subject olfactory memory en_US
dc.subject patient monitoring en_US
dc.subject postoperative period en_US
dc.subject preoperative period en_US
dc.subject prospective study en_US
dc.subject Review en_US
dc.subject agnosia en_US
dc.subject analogs and derivatives en_US
dc.subject chemically induced en_US
dc.subject drug effects en_US
dc.subject memory en_US
dc.subject Agnosia en_US
dc.subject Anesthesia Recovery Period en_US
dc.subject Anesthetics, Inhalation en_US
dc.subject Humans en_US
dc.subject Isoflurane en_US
dc.subject Memory en_US
dc.subject Postoperative Period en_US
dc.subject Prospective Studies en_US
dc.title The effect of desflurane on postoperative olfactory memory en_US
dc.type Review en_US
dc.identifier.volume 20 en_US
dc.identifier.issue 10 en_US
dc.identifier.startpage 2163
dc.identifier.startpage 2163 en_US
dc.identifier.endpage 2167 en_US
dc.relation.publicationcategory Diğer en_US
dc.identifier.pmid 27249619 en_US
dc.identifier.wos WOS:000382459500034 en_US

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