DSpace Repository

Manual thrombus aspiration and the improved survival of patients with unstable angina pectoris treated with percutaneous coronary intervention (30 months follow-up)

Show simple item record

dc.contributor.author Yıldız, Bekir Serhat
dc.contributor.author Bilgin, M.
dc.contributor.author Zungur, M.
dc.contributor.author Alihanoglu, Yusuf İzzettin
dc.contributor.author Kılıç, İsmail Doğu
dc.contributor.author Buber, İpek
dc.contributor.author Ergin, Ahmet
dc.contributor.author Kaftan, Havane Asuman
dc.contributor.author Evrengül, Harun
dc.date.accessioned 2019-08-16T13:03:55Z
dc.date.available 2019-08-16T13:03:55Z
dc.date.issued 2016
dc.identifier.issn 00257974 (ISSN)
dc.identifier.uri http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/9651
dc.description.abstract The clinical effect of intracoronary thrombus aspiration during percutaneous coronary intervention in patients with unstable angina pectoris is unknown. In this study, we aimed to assess how thrombus aspiration during percutaneous coronary intervention affects in-hospital and 30-month mortality and complications in patients with unstable angina pectoris. We undertook an observational cohort study of 645 consecutive unstable angina pectoris patients who had performed percutaneous coronary intervention from February 2011 to March 2013. Before intervention, 159 patients who had culprit lesion with thrombus were randomly assigned to group 1 (thrombus aspiration group) and group 2 (stand-alone percutaneous coronary intervention group). All patients were followed-up 30 months until August 2015. Thrombus aspiration was performed in 64 patients (46%) whose cardiac markers (ie, creatinine kinase [CK-MB] mass and troponin T) were significantly lower after percutaneous coronary intervention than in those of group 2 (CK-MB mass: 3.801.11 vs 4.230.89, P=0.012; troponin T: 0.0120.014 vs 0.0180.008, P=0.002). Left ventricular ejection fraction at 6, 12, and 24 months postintervention was significantly higher in the group 1. During a mean followup period of 28.876.28 months, mortality rates were 6.3% in the group 1 versus 12.9% in the group 2. Thrombus aspiration was also associated with significantly less long-term mortality in unstable angina pectoris patients (adjusted HR: 4.61, 95% CI: 1.16-18.21, P=0.029). Thrombus aspiration in the context of unstable angina pectoris is associated with a limited elevation in cardiac enzymes during intervention that minimises microembolization and significantly improves both of epicardial flow and myocardial perfusion, as shown by angiographic TIMI flow grade and frame count. Thrombus aspiration during percutaneous coronary intervention in unstable angina pectoris patients has better survival over a 30-month follow-up period. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.
dc.language.iso English
dc.publisher Lippincott Williams and Wilkins
dc.relation.isversionof 10.1097/MD.0000000000002919
dc.rights info:eu-repo/semantics/openAccess
dc.subject creatine kinase MB
dc.subject troponin T
dc.subject biological marker
dc.subject adult
dc.subject aged
dc.subject Article
dc.subject atrial fibrillation
dc.subject cohort analysis
dc.subject female
dc.subject follow up
dc.subject heart infarction
dc.subject heart left ventricle ejection fraction
dc.subject heart tamponade
dc.subject heart ventricle fibrillation
dc.subject human
dc.subject major clinical study
dc.subject male
dc.subject middle aged
dc.subject mortality
dc.subject mortality rate
dc.subject observational study
dc.subject percutaneous coronary intervention
dc.subject priority journal
dc.subject retrospective study
dc.subject stent thrombosis
dc.subject survival
dc.subject thrombus aspiration
dc.subject unstable angina pectoris
dc.subject Angina, Unstable
dc.subject blood
dc.subject clinical trial
dc.subject coronary angiography
dc.subject Coronary Thrombosis
dc.subject echocardiography
dc.subject electrocardiography
dc.subject multicenter study
dc.subject multimodality cancer therapy
dc.subject postoperative complication
dc.subject procedures
dc.subject survival rate
dc.subject thrombectomy
dc.subject treatment outcome
dc.subject Aged
dc.subject Biomarkers
dc.subject Combined Modality Therapy
dc.subject Coronary Angiography
dc.subject Echocardiography
dc.subject Electrocardiography
dc.subject Female
dc.subject Follow-Up Studies
dc.subject Humans
dc.subject Male
dc.subject Middle Aged
dc.subject Percutaneous Coronary Intervention
dc.subject Postoperative Complications
dc.subject Retrospective Studies
dc.subject Survival Rate
dc.subject Thrombectomy
dc.subject Treatment Outcome
dc.title Manual thrombus aspiration and the improved survival of patients with unstable angina pectoris treated with percutaneous coronary intervention (30 months follow-up)
dc.type Article
dc.relation.journal Medicine (United States)
dc.contributor.authorID 0000000178100624
dc.contributor.authorID 0000-0002-5270-3897
dc.contributor.authorID 0000-0001-5236-7507
dc.contributor.authorID 0000-0002-0705-7726
dc.identifier.volume 95
dc.identifier.issue 8
dc.relation.publicationCategory Uluslararası Hakemli Dergi
dc.identifier.index Scopus
dc.identifier.index WOS
dc.identifier.index PubMed

Files in this item

This item appears in the following Collection(s)

Show simple item record