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Effectiveness of palatal mucosa graft in surgical treatment of sub-glottic stenosis

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dc.contributor.author Aydogmus, U.
dc.contributor.author Topkara, A.
dc.contributor.author Akbulut, M.
dc.contributor.author Ozkan, A.
dc.contributor.author Turk, F.
dc.contributor.author Sahin, B.
dc.contributor.author Yuncu, G.
dc.date.accessioned 2019-08-16T13:00:02Z
dc.date.available 2019-08-16T13:00:02Z
dc.date.issued 2016
dc.identifier.issn 19768710 (ISSN)
dc.identifier.uri http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/9341
dc.description.abstract Objectives. Mucosal free grafts may be successfully applied in many surgical interventions. This study aims at investigating the feasibility of palatal mucosa graft in sub-glottic field in an animal model. Methods. This randomized prospective controlled study was conducted with an animal model. Sub-glottic inflammation was created in 15 adult rabbits in each group and sub-glottic stenosis surgery was applied thereafter. The rabbits in group 1 (control group) underwent segmental resection, partial cricoidectomy, and trachea-thyroid cartilage anasto¬mosis; the rabbits in group 2 underwent segmental resection, cricoplasty, and crico-tracheal anastomosis using free buccal mucosa graft; and the rabbits in group 3 underwent segmental resection, cricoplasty, and crico-tracheal anastomosis using free palatal mucosa graft. Restenosis was evaluated after 42 days. Results. The percentages of stenosis were 27%±20%, 40%±20%, and 34%±23% for group 1, 2, and 3, respectively and the difference was not statistically significant (P=0.29). Intensive and tight fibrosis was observed in 2 rabbits (13%) in group 1, in 5 rabbits (33%) in group 2, and in 3 rabbits (20%) in group 3. There was not a statistically significant difference between groups (P=0.41). Excessive inflammation was observed in 3 rabbits (20%) in group 1, in 7 rabbits (47%) in group 2, and 3 rabbits (20%) in group 3. There was no a statistically significant difference between groups although inflammation rate was higher in the rabbits which underwent buccal mucosa graft (P=0.18). Conclusion. The surgical treatments applied with free mucosa graft reduced anastomosis tension through enabling anasto¬mosis to the distal of cricoid instead of thyroid cartilage. Free palatal mucosa grafts may be used in sub-glottic field, one of the most challenging fields of trachea surgery, due to ease of application and rapid vascularization. © 2016 by Korean Society of Otorhinolaryngology-Head and Neck Surgery.
dc.language.iso English
dc.publisher Korean Society of Otolaryngology
dc.relation.isversionof 10.21053/ceo.2015.01508
dc.subject Airway
dc.subject Autografts
dc.subject Mucosal tissues
dc.subject Tracheal stenosis
dc.subject Wound healing
dc.title Effectiveness of palatal mucosa graft in surgical treatment of sub-glottic stenosis
dc.type Article
dc.relation.journal Clinical and Experimental Otorhinolaryngology
dc.identifier.volume 9
dc.identifier.issue 4
dc.identifier.startpage 358
dc.identifier.endpage 365
dc.identifier.index Scopus


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