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A new method for evaluation of the autonomic nervous system in patients with idiopathic hyperhidrosis: systolic blood pressure and heart rate recovery after graded exercise

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dc.contributor.author Alihanoğlu, Yusuf İzzettin
dc.contributor.author Yıldız, Bekir Serhat
dc.contributor.author Kılıç, İsmail Doğu
dc.contributor.author Sarıçopur, Ahmet
dc.contributor.author Öncü, Mustafa
dc.contributor.author Büber, İpek
dc.contributor.author Taşlı, Levent
dc.contributor.author Evrengül, Havva
dc.date.accessioned 2019-08-16T12:59:56Z
dc.date.available 2019-08-16T12:59:56Z
dc.date.issued 2016
dc.identifier.issn 03076938 (ISSN)
dc.identifier.uri http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/9331
dc.description.abstract Background: Idiopathic hyperhidrosis (IH) is characterized by excessive and uncontrolled production of sweat, mainly localized to the soles, palms, axillae and craniofacial area. Although IH is a disease concerning the autonomic nervous system, it is not clear yet whether this dysfunction is local or systemic. Objective: To evaluate the autonomic control of cardiovascular system by measuring values of heart rate recovery (HRR) and systolic blood pressure recovery (SBPR) obtained at various time intervals after maximal graded exercise treadmill testing in patients with IH compared with controls. Methods: The study population comprised 36 patients with IH (20 men, 16 women; mean age 25 ± 7 years) and 36 healthy controls (HCs) (12 men, 24 women; mean age 27 ± 5 years). All patients were selected from young, nonobese and healthy sedentary individuals. Results: Peak HR values reached in patients with IH were significantly higher compared with the HC group (P < 0.001). The obtained HRR values at minutes 3, 4 and 5 were significantly lower in the IH than the HC group [57 ± 16 vs. 64 ± 9 (P = 0.03); 61 ± 14 vs. 68 ± 9 (P = 0.03); 64 ± 12 vs. 70 ± 7 (P < 0.01)]. In addition, calculated mean values for SBPR1 and SBPR2 were > 1 in patients with IH (1.04 ± 0.15 vs. 0.98 ± 0.08 and 1.0 ± 0.12 vs. 0.94 ± 0.06, respectively) and these were statistically significant compared with the HC group (P = 0.04 and P = 0.03, respectively). Conclusions: The significantly impaired SBPR and decreased HRR values we observed in patients with IH may indicate that the autonomic dysfunction in IH is a systemic disorder with cardiovascular effects, rather than a merely local disease. Both HRR and SBPR values may provide additional information about predicting adverse cardiovascular events in the future even in apparently healthy young patients with IH. © 2016 British Association of Dermatologists
dc.language.iso English
dc.publisher Blackwell Publishing Ltd
dc.relation.isversionof 10.1111/ced.12915
dc.rights info:eu-repo/semantics/closedAccess
dc.subject glucose
dc.subject hemoglobin
dc.subject adult
dc.subject Article
dc.subject autonomic dysfunction
dc.subject autonomic nervous system
dc.subject cardiovascular parameters
dc.subject cardiovascular system
dc.subject clinical article
dc.subject clinical assessment
dc.subject clinical evaluation
dc.subject comparative study
dc.subject controlled study
dc.subject convalescence
dc.subject diastolic blood pressure
dc.subject female
dc.subject heart rate
dc.subject heart rate recovery
dc.subject human
dc.subject hyperhidrosis
dc.subject idiopathic disease
dc.subject idiopathic hyperhidrosis
dc.subject male
dc.subject medical examination
dc.subject population
dc.subject priority journal
dc.subject sedentary lifestyle
dc.subject systolic blood pressure
dc.subject systolic blood pressure recovery
dc.subject treadmill exercise
dc.subject treadmill test
dc.subject adolescent
dc.subject blood pressure
dc.subject case control study
dc.subject exercise
dc.subject exercise test
dc.subject middle aged
dc.subject pathophysiology
dc.subject physiology
dc.subject procedures
dc.subject young adult
dc.subject Adolescent
dc.subject Adult
dc.subject Autonomic Nervous System
dc.subject Blood Pressure
dc.subject Case-Control Studies
dc.subject Exercise
dc.subject Exercise Test
dc.subject Female
dc.subject Heart Rate
dc.subject Humans
dc.subject Hyperhidrosis
dc.subject Male
dc.subject Middle Aged
dc.subject Young Adult
dc.title A new method for evaluation of the autonomic nervous system in patients with idiopathic hyperhidrosis: systolic blood pressure and heart rate recovery after graded exercise
dc.type Article
dc.relation.journal Clinical and Experimental Dermatology
dc.contributor.authorID 0000-0002-5270-3897
dc.contributor.authorID 0000000178100624
dc.contributor.authorID 0000-0002-2661-1147
dc.contributor.authorID 0000-0003-2457-313X
dc.contributor.authorID 0000-0002-5433-4394
dc.identifier.volume 41
dc.identifier.issue 8
dc.identifier.startpage 847
dc.identifier.endpage 851
dc.relation.publicationCategory Uluslararası Hakemli Dergi
dc.identifier.index Scopus
dc.identifier.index WOS
dc.identifier.index PubMed

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