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Acute improvement of pulmonary artery pressure by non-invasive positive pressure ventilation in the patients with hypercapnic respiratory failure

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dc.contributor.author Dursunoǧlu, N.
dc.contributor.author Dursunoǧlu, D.
dc.contributor.author Moray, A.
dc.contributor.author Gür, Ş.
dc.date.accessioned 2019-08-16T12:04:53Z
dc.date.available 2019-08-16T12:04:53Z
dc.date.issued 2010
dc.identifier.issn 04941373 (ISSN)
dc.identifier.uri http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/6187
dc.description.abstract It is very important to decrease pulmonary artery pressure (PAP) in patients with chronic obstructive pulmonary disease (COPD) in order to prevent progression to right heart failure. We showed an acute improvement of PAP by non-invasive positive pressure ventilation (NPPV) treatment in patients with hypercapnic respiratory failure. In 26 patients with COPD (18 males and 8 females), physical examination, Doppler echocardiographic evaluation and arterial blood gases analysis were performed on admission and at discharge. PAP was measured by Doppler echocardiography. NPPV was used when 2 of the following were present without contraindications: 1. Respiratory distress with moderate to severe dyspnea, 2. Arterial pH less than 7.35 with PaCO2 above 45 mmHg, 3. Respiratory rate of 25/minute or greater. Mean age of the patients was 62.6 ± 10.8 year, and mean usage of the NPPV was 12.6 ± 5.5 day. Mean and systolic PAPs of the patients (43.8 ± 16.9 mmHg and 66.7 ± 23.3 mmHg) were significantly decreased with NPPV treatment (26.6 ± 8.4 mmHg, p< 0.0001 and 41.8 ± 14.6 mmHg, p< 0.0001). Also, each parameter of the arterial blood gases was improved significantly with NPPV usage. An echocardiographic assessment in the COPD patients having NPPV treatment due to acute respiratory failure, might be a useful and easy method to show an improvement of PAP as a supportive measure in the management of those patients, in addition to beneficial effects of that treatment on respiratory acidosis, hypercapnia and hypoxemia.
dc.language.iso English
dc.subject Chronic obstructive pulmonary disease
dc.subject Echocardiography
dc.subject Non-invasive positive pressure ventilation
dc.subject Pulmonary arterial pressure
dc.subject Respiratory failure
dc.subject adult
dc.subject arterial pH
dc.subject article
dc.subject assisted ventilation
dc.subject blood gas
dc.subject breathing rate
dc.subject carbon dioxide tension
dc.subject chronic obstructive lung disease
dc.subject clinical article
dc.subject controlled study
dc.subject disease severity
dc.subject Doppler echocardiography
dc.subject female
dc.subject heart failure
dc.subject human
dc.subject hypercapnia
dc.subject hypoxemia
dc.subject lung artery pressure
dc.subject male
dc.subject non invasive positive pressure ventilation
dc.subject physical examination
dc.subject respiratory acidosis
dc.subject respiratory distress
dc.subject respiratory failure
dc.subject treatment outcome
dc.subject Female
dc.subject Humans
dc.subject Hypercapnia
dc.subject Male
dc.subject Middle Aged
dc.subject Positive-Pressure Respiration
dc.subject Pulmonary Artery
dc.subject Pulmonary Disease, Chronic Obstructive
dc.subject Pulmonary Wedge Pressure
dc.subject Respiratory Function Tests
dc.subject Respiratory Insufficiency
dc.subject Treatment Outcome
dc.title Acute improvement of pulmonary artery pressure by non-invasive positive pressure ventilation in the patients with hypercapnic respiratory failure
dc.type Article
dc.relation.journal Tuberkuloz ve Toraks
dc.identifier.volume 58
dc.identifier.issue 4
dc.identifier.startpage 418
dc.identifier.endpage 424
dc.identifier.index Scopus


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