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Effects of single-dose steroid usage on edema, ecchymosis, and intraoperative bleeding in rhinoplasty

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dc.contributor.author Kara, Cüneyt Orhan
dc.contributor.author Gökalan, İnci
dc.date.accessioned 2019-08-16T11:50:25Z
dc.date.available 2019-08-16T11:50:25Z
dc.date.issued 1999
dc.identifier.issn 0032-1052
dc.identifier.uri https://hdl.handle.net/11499/5604
dc.identifier.uri https://doi.org/10.1097/00006534-199912000-00041
dc.description.abstract To examine the effects of single-dose dexamethasone use on edema, ecchymosis, and intraoperative bleeding in rhinoplasty, a double-blind, randomized trial with placebo control was planned. A total of 55 consecutive patients were included in the study. The dexamethasone (10 mg) was given intravenously just before surgery (preoperative group, n=18) or at the end of surgery (postoperative group, n=20). In the placebo group, 17 patients received saline preoperatively or postoperatively. Intraoperative blood loss was recorded for each patient. Postoperative scoring of eyelid swelling and ecchymosis was begun after approximately 24 hours and lasted into postoperative day 9. Only for the first 2 days was the difference between steroid groups (preoperative and postoperative) and the placebo group statistically significant for a decrease in eyelid edema (p < 0.05). A statistically significant difference in upper eyelid ecchymosis for both preoperative and postoperative steroid groups versus the placebo group also existed in the first 2 days (p < 0.05). Preoperative or postoperative steroid administration had no influence on the ecchymosis of the lower eyelid. When the results of the preoperative and postoperative steroid groups were compared, no significant difference was detected between the two groups in either edema or ecchymosis. To determine whether steroid use shortened the recovery period, the days on which edema and ecchymosis reached a minimum level were compared among the groups; no statistically significant difference was found among them. Using single-dose dexamethasone preoperatively did not alter intraoperative blood loss. Use of single-dose dexamethasone (either preoperatively or postoperatively) in rhinoplasty has a significant effect in decreasing upper and lower eyelid edema and upper eyelid ecchymosis for the first 2 days when compared with a placebo group. However, the effect of dexamethasone was lost after the first 2 days, and its use did not shorten the recovery period. en_US
dc.language.iso en en_US
dc.publisher Lippincott Williams and Wilkins en_US
dc.relation.ispartof Plastic and Reconstructive Surgery en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject dexamethasone en_US
dc.subject steroid en_US
dc.subject adult en_US
dc.subject article en_US
dc.subject bleeding en_US
dc.subject clinical trial en_US
dc.subject controlled clinical trial en_US
dc.subject controlled study en_US
dc.subject double blind procedure en_US
dc.subject drug effect en_US
dc.subject ecchymosis en_US
dc.subject eyelid edema en_US
dc.subject female en_US
dc.subject human en_US
dc.subject intravenous drug administration en_US
dc.subject major clinical study en_US
dc.subject male en_US
dc.subject nose reconstruction en_US
dc.subject postoperative period en_US
dc.subject preoperative period en_US
dc.subject priority journal en_US
dc.subject randomized controlled trial en_US
dc.subject steroid therapy en_US
dc.title Effects of single-dose steroid usage on edema, ecchymosis, and intraoperative bleeding in rhinoplasty en_US
dc.type Article en_US
dc.identifier.volume 104 en_US
dc.identifier.issue 7 en_US
dc.identifier.startpage 2213
dc.identifier.startpage 2213 en_US
dc.identifier.endpage 2218 en_US
dc.authorid 0000-0003-2219-4283
dc.authorid 0000-0002-4701-638X
dc.identifier.doi 10.1097/00006534-199912000-00041
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.identifier.pmid 11149790 en_US
dc.identifier.scopus 2-s2.0-0344806288 en_US
dc.identifier.wos WOS:000083854900042 en_US

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