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Low dose sultamicillin in acute sinusitis

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dc.contributor.author Topuz, Bülent
dc.contributor.author Katircio?lu, O.
dc.contributor.author Bayramo?lu, I.
dc.contributor.author Ardiç, F.N.
dc.contributor.author Erbudak, H.
dc.date.accessioned 2019-08-16T11:46:01Z
dc.date.available 2019-08-16T11:46:01Z
dc.date.issued 2002
dc.identifier.issn 1124-9390
dc.identifier.uri https://hdl.handle.net/11499/5383
dc.description.abstract Objectives: to study the effectiveness of low dose sultamicillin in the treatment of acute sinusitis. Methods: a total of 108 patients, between 16-56 years of age (mean 32.8), suffering from acute sinusitis took part in the trial. Patients received orally 2×375 mg sultamicillin, and compared with patients receiving 3×500 mg amoxicillin. The first control was made between the 5th and 7th days. A patient was considered clinically cured when all pretreatment signs and symptoms of infection were eliminated. Clinical improvement was defined as the partial disappearance of pretreatment signs and symptoms. In either result, study drugs were reconstituted for additional 5 days. Failure was defined as no change or worsening of signs and symptoms; and study drug was changed. The second control was made between 10-12th days, and the third was four weeks later. Results: The clinical success (improvement + cure) rate was (17+11)/42 (66.6%) and (28+21)/66 (74.2%) for amoxicillin and sultamicillin respectively, at first control. All improved patients were cured at the second control. No significant side-effects were noted in either amoxicillin or sultamicillin treated patients. All side effects were gastrointestinal, 11.9% and 3.0% in the same order. Conclusions: Low dose sultamicillin was comparable to amoxicillin; sultamicillin has fewer side effects than amoxicillin (p>O.05). en_US
dc.language.iso en en_US
dc.relation.ispartof Infezioni in Medicina en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Acute sinusitis en_US
dc.subject Amoxicillin en_US
dc.subject Sultamicillin en_US
dc.subject amoxicillin en_US
dc.subject sultamicillin en_US
dc.subject acute disease en_US
dc.subject adolescent en_US
dc.subject adult en_US
dc.subject antibiotic therapy en_US
dc.subject article en_US
dc.subject clinical feature en_US
dc.subject clinical trial en_US
dc.subject controlled clinical trial en_US
dc.subject controlled study en_US
dc.subject disease severity en_US
dc.subject drug efficacy en_US
dc.subject female en_US
dc.subject gastrointestinal symptom en_US
dc.subject human en_US
dc.subject major clinical study en_US
dc.subject male en_US
dc.subject sinusitis en_US
dc.subject treatment failure en_US
dc.subject treatment outcome en_US
dc.subject Acute Disease en_US
dc.subject Adolescent en_US
dc.subject Adult en_US
dc.subject Ampicillin en_US
dc.subject Anti-Bacterial Agents en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Single-Blind Method en_US
dc.subject Sinusitis en_US
dc.subject Sulbactam en_US
dc.title Low dose sultamicillin in acute sinusitis en_US
dc.type Article en_US
dc.identifier.volume 10 en_US
dc.identifier.issue 1 en_US
dc.identifier.startpage 45
dc.identifier.startpage 45 en_US
dc.identifier.endpage 48 en_US
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US

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