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Are tonsils a reservoir for Helicobacter pylori infection in children?

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dc.contributor.author Yılmaz, Mustafa
dc.contributor.author Kara, C.O.
dc.contributor.author Kaleli, İlknur
dc.contributor.author Demir, Melek
dc.contributor.author Tümkaya, F.
dc.contributor.author Büke, A.S.
dc.contributor.author Topuz, Bülent
dc.date.accessioned 2019-08-16T11:42:10Z
dc.date.available 2019-08-16T11:42:10Z
dc.date.issued 2004
dc.identifier.issn 0165-5876
dc.identifier.uri https://hdl.handle.net/11499/5155
dc.identifier.uri https://doi.org/10.1016/j.ijporl.2003.10.016
dc.description.abstract Objective: Helicobacter pylori (H. Pylori) has been associated with the development of gastritis, peptic ulcer and gastric cancer. Although H. pylori infects up to more than half of the world's population, to date the precise modes of transmission has not been fully understood yet. Therefore a study was planned to investigate whether the tonsils and the adenoid tissue were the reservoir or the gate for the entrance of H. pylori. Methods: The adenotonsillectomy specimens obtained from 50 children, between two and 10 years of age were examined for H. Pylori colonization by the CLO-test method. Before tonsillectomy, anti-H. pylori IgG antibody titers were detected by commercial enzyme immunoassay method in venous blood and H. pylori antigen enzyme immunoassay for detection of H. pylori in stool was used to define current infection status. Results: The stool antigen was positive in 25 (50%) of 50 children. Serum IgG antibody was positive in 28 (56%) patients and both tests were positive in 21 (42%) patients. H. pylori positivity was not detected in any one of the adenotonsillectomy specimens with the CLO-test method. Conclusion: In this study although H. pylori was detected in stools of children, it was not detected in adenotonsillectomy specimens with CLO-test method. The results may indicate that H. pylori does not colonize in either adenoid or tonsils and that these tissues do not constitute a reservoir for H. pylori infection. © 2003 Elsevier Ireland Ltd. All rights reserved. en_US
dc.language.iso en en_US
dc.publisher Elsevier Ireland Ltd en_US
dc.relation.ispartof International Journal of Pediatric Otorhinolaryngology en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject H. pylori en_US
dc.subject Serological test en_US
dc.subject Stool antigen en_US
dc.subject Tonsils en_US
dc.subject antibody en_US
dc.subject antigen en_US
dc.subject adenoid en_US
dc.subject adenotonsillectomy en_US
dc.subject analytic method en_US
dc.subject antibody detection en_US
dc.subject antibody titer en_US
dc.subject article en_US
dc.subject bacterial colonization en_US
dc.subject child en_US
dc.subject clinical article en_US
dc.subject controlled study en_US
dc.subject enzyme immunoassay en_US
dc.subject feces analysis en_US
dc.subject female en_US
dc.subject Helicobacter infection en_US
dc.subject Helicobacter pylori en_US
dc.subject human en_US
dc.subject male en_US
dc.subject priority journal en_US
dc.subject tonsil en_US
dc.subject tonsillectomy en_US
dc.subject venous blood en_US
dc.title Are tonsils a reservoir for Helicobacter pylori infection in children? en_US
dc.type Article en_US
dc.identifier.volume 68 en_US
dc.identifier.issue 3 en_US
dc.identifier.startpage 307
dc.identifier.startpage 307 en_US
dc.identifier.endpage 310 en_US
dc.identifier.doi 10.1016/j.ijporl.2003.10.016
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.identifier.pmid 15129940 en_US
dc.identifier.scopus 2-s2.0-1042287049 en_US
dc.identifier.wos WOS:000189097400005 en_US

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