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Immunohistochemical detection of 1,25-dihydroxyvitamin D receptor in rat vaginal epithelium

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dc.contributor.author Yıldırım, Başak
dc.contributor.author Abban, Gülçin
dc.contributor.author Erdogan, B.S.
dc.date.accessioned 2019-08-16T11:39:55Z
dc.date.available 2019-08-16T11:39:55Z
dc.date.issued 2004
dc.identifier.issn 0015-0282
dc.identifier.uri https://hdl.handle.net/11499/5005
dc.identifier.uri https://doi.org/10.1016/j.fertnstert.2004.07.949
dc.description.abstract To determine the distribution of 1,25-dihydroxyvitamin D receptor (VDR) in rat vaginal epithelium during the estrus cycle and in ovariectomized rats. Animal study performed in two groups of rats. The expression of VDR was examined in the first group during the estrous cycle and in the second group after ovariectomy. University animal laboratory. Balb/c female rats. Vaginas were removed and processed for immunohistochemical analysis. We recorded the localization, distribution, and expression of VDR in vaginal epithelium during the rat estrus cycle and in ovariectomized rats. In cyclic rats, VDR was detected in basal and suprabasal cells during all of the cycle periods. In apical cells, VDR was positive in diestrus and estrus but negative in proestrous. In ovariectomized rats, VDR was not detected in any layers of vaginal epithelium. In vaginal epithelium, the presence of VDR was shown by using immunohistochemical techniques. During the estrous cycle, VDR has an important role in the proliferation and differentiation of vaginal squamous epithelium that is similar to the effects of estrogen. © 2004 by American Society for Reproductive Medicine. en_US
dc.language.iso en en_US
dc.relation.ispartof Fertility and Sterility en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject epithelium en_US
dc.subject receptor en_US
dc.subject Vagina en_US
dc.subject vitamin D en_US
dc.subject vitamin D receptor en_US
dc.subject animal tissue en_US
dc.subject article en_US
dc.subject basal cell en_US
dc.subject cell differentiation en_US
dc.subject cell proliferation en_US
dc.subject controlled study en_US
dc.subject diestrus en_US
dc.subject estrus en_US
dc.subject estrus cycle en_US
dc.subject female en_US
dc.subject immunohistochemistry en_US
dc.subject nonhuman en_US
dc.subject ovariectomy en_US
dc.subject priority journal en_US
dc.subject proestrus en_US
dc.subject protein analysis en_US
dc.subject protein expression en_US
dc.subject protein function en_US
dc.subject protein localization en_US
dc.subject rat en_US
dc.subject vagina epithelium en_US
dc.subject Animals en_US
dc.subject Cell Differentiation en_US
dc.subject Cell Division en_US
dc.subject Epithelial Cells en_US
dc.subject Epithelium en_US
dc.subject Estrus en_US
dc.subject Female en_US
dc.subject Immunohistochemistry en_US
dc.subject Ovariectomy en_US
dc.subject Rats en_US
dc.subject Rats, Inbred Strains en_US
dc.subject Receptors, Calcitriol en_US
dc.subject Tissue Distribution en_US
dc.title Immunohistochemical detection of 1,25-dihydroxyvitamin D receptor in rat vaginal epithelium en_US
dc.type Article en_US
dc.identifier.volume 82 en_US
dc.identifier.issue 6 en_US
dc.identifier.startpage 1602
dc.identifier.startpage 1602 en_US
dc.identifier.endpage 1608 en_US
dc.identifier.doi 10.1016/j.fertnstert.2004.07.949
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.identifier.pmid 15589866 en_US
dc.identifier.scopus 2-s2.0-10044247510 en_US
dc.identifier.wos WOS:000225802300020 en_US

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