DSpace Repository

Prognostic value of CHA(2)DS(2)-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation

Show simple item record

dc.contributor.author Akboga, Mehmet Kadri
dc.contributor.author Yilmaz, Samet
dc.contributor.author Yalcin, Ridvan
dc.date.accessioned 2023-01-09T21:09:29Z
dc.date.available 2023-01-09T21:09:29Z
dc.date.issued 2021
dc.identifier.issn 2149-2263
dc.identifier.issn 2149-2271
dc.identifier.uri https://doi.org/10.5152/AnatolJCardiol.2021.03982
dc.identifier.uri https://search.trdizin.gov.tr/yayin/detay/488122
dc.identifier.uri http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/46100
dc.description.abstract Objective: To evaluate the prognostic value of preprocedural CHA(2)DS(2)-VASc [congestive heart failure, hypertension, age >= 75 years (doubled), diabetes mellitus, previous stroke or transient ischemic attack (TIA) (doubled), vascular disease, age 65-74 years, female gender] score in predicting high SYNTAX (Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) score and in-hospital mortality for non-atrial fibrillation (AF) patients presenting with non-ST elevation myocardial infarction (NSTEMI). The CHA(2)DS(2)-VASc score used to determine thromboembolic risks in AF was recently reported to predict major adverse clinical outcomes in patients with the acute coronary syndrome, irrespective of AF. Methods: A total of 906 patients with a diagnosis of NSTEMI who underwent coronary angiography were retrospectively enrolled and divided into three groups according to their SYNTAX scores (low, intermediate, and high). The CHA(2)DS(2)-VASc score of each patient was calculated. Results: SYNTAX score had a significant positive correlation with the CHA(2)DS(2)-VASc score (r=0.320; p<0.001) in the Spearman correlation analysis. The CHA(2)DS(2)-VASc score [Odds ratio, 1.445; 95% confidence interval (CI), 1.268-1.648, p<0.001], left ventricular ejection fraction, creatinine, C-reactive protein, and high-density and low-density lipoprotein cholesterol levels were demonstrated to be independent predictors of high SYNTAX score. The CHA(2)DS(2)-VASc score [Hazard ratio (HR), 1.867; 95% CI: 1.462-2.384; p<0.001], the SYNTAX score (HR, 1.049; p=0.003), and age (HR, 1.057; p=0.002) were independently associated with higher risk of in-hospital mortality in a multiple Cox-regression model. KaplanMeier survival curves stratified by the CHA(2)DS(2)-VASc score (<4 vs. >= 4) also showed that higher CHA(2)DS(2)-VASc scores were associated with higher in-hospital mortality. Conclusions: In non-AF patients with NSTEMI, CHA(2)DS(2)-VASc and SYNTAX scores are useful for prognosis assessment and can be used to identify patients at higher risk for in-hospital mortality. en_US
dc.language.iso en en_US
dc.publisher Aves en_US
dc.relation.ispartof Anatolian Journal Of Cardiology en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject CHA(2)DS(2)-VASc score en_US
dc.subject coronary atherosclerotic burden en_US
dc.subject in-hospital mortality en_US
dc.subject prognosis en_US
dc.subject NSTEMI en_US
dc.subject Percutaneous Coronary Intervention en_US
dc.subject Acute Catheterization en_US
dc.subject Artery-Disease en_US
dc.subject Stratification en_US
dc.subject Outcomes en_US
dc.title Prognostic value of CHA(2)DS(2)-VASc score in predicting high SYNTAX score and in-hospital mortality for non-ST elevation myocardial infarction in patients without atrial fibrillation en_US
dc.type Article en_US
dc.identifier.volume 25 en_US
dc.identifier.issue 11 en_US
dc.identifier.startpage 789 en_US
dc.identifier.endpage 795 en_US
dc.identifier.doi 10.5152/AnatolJCardiol.2021.03982
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.authorscopusid 41261015400
dc.authorscopusid 55358223600
dc.authorscopusid 6701440418
dc.department-temp [Akboga, Mehmet Kadri; Yalcin, Ridvan] Gazi Univ, Fac Med, Dept Cardiol, Ankara, Turkey; [Yilmaz, Samet] Pamukkale Univ, Fac Med, Dept Cardiol, Denizli, Turkey en_US
dc.identifier.pmid 34734812 en_US
dc.identifier.scopus 2-s2.0-85110294792 en_US
dc.identifier.trdizinid 488122 en_US
dc.identifier.wos WOS:000715731900006 en_US

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record