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Anticandidal activity of Pseudomonas aeruginosa strains isolated from clinical specimens

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dc.contributor.author Kaleli, İlknur.
dc.contributor.author Cevahir, Nural.
dc.contributor.author Demir, Melek.
dc.contributor.author Yıldırım, Umut.
dc.contributor.author Şahin, Rasim.
dc.date.accessioned 2019-08-16T11:33:44Z
dc.date.available 2019-08-16T11:33:44Z
dc.date.issued 2007
dc.identifier.issn 0933-7407
dc.identifier.uri https://hdl.handle.net/11499/4374
dc.identifier.uri https://doi.org/10.1111/j.1439-0507.2006.01322.x
dc.description.abstract Pseudomonads represent the major group of non-differentiating microorganisms that produce antibiotics. The antibiotic substances produced by this group of organisms are pyocyanin, pyrolnitrin and pseudomonic acid. This study was designed to investigate the in vivo and in vitro anticandidal activity of Pseudomonas aeruginosa strains against Candida species. Forty-four P. aeruginosa strains isolated from various specimens of intensive care patients were included in the study. All P. aeruginosa strains have pyocyanin pigment. Candida albicans ATCC 10231, Candida parapsilosis ATCC 22019, Candida krusei ATCC 6258 and a clinical isolate of Candida tropicalis were used to measure the anticandidal activity of Pseudomonas strains by Kerr's method. The total inhibition rates obtained by using blood agar of C. albicans, C. parapsilosis, C. krusei and C. tropicalis were 41%, 34%, 34% and 25% respectively. When Sabouraud dextrose agar (SDA) was used, the rates were detected as 45%, 39%, 48% and 25% respectively. In the mouse model of concomitant subcutaneous infection with Candida species and P. aeruginosa no yeast were recovered from skin cultures despite 100% detection of P. aeruginosa. Pseudomonas aeruginosa strains isolated from intensive care patients showed anticandidal activity against the Candida species in the present study and this point may be important in the following and treatment of patients. © 2006 Blackwell Publishing Ltd. en_US
dc.language.iso en en_US
dc.relation.ispartof Mycoses en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Anticandidal activity en_US
dc.subject Candida species en_US
dc.subject Pseudomonas aeruginosa en_US
dc.subject agar en_US
dc.subject pyocyanine en_US
dc.subject animal model en_US
dc.subject antifungal activity en_US
dc.subject article en_US
dc.subject bacterial strain en_US
dc.subject bacterium isolate en_US
dc.subject bacterium isolation en_US
dc.subject Candida albicans en_US
dc.subject Candida krusei en_US
dc.subject Candida parapsilosis en_US
dc.subject Candida tropicalis en_US
dc.subject fungus isolation en_US
dc.subject in vitro study en_US
dc.subject in vivo study en_US
dc.subject inhibition kinetics en_US
dc.subject intensive care en_US
dc.subject mouse en_US
dc.subject nonhuman en_US
dc.subject patient care en_US
dc.subject priority journal en_US
dc.subject tissue section en_US
dc.subject yeast en_US
dc.subject Animals en_US
dc.subject Antibiosis en_US
dc.subject Candida en_US
dc.subject Candidiasis en_US
dc.subject Culture Media en_US
dc.subject Dermatomycoses en_US
dc.subject Humans en_US
dc.subject Mice en_US
dc.subject Mice, Inbred BALB C en_US
dc.subject Pseudomonas Infections en_US
dc.subject Issatchenkia orientalis en_US
dc.subject Pseudomonas en_US
dc.title Anticandidal activity of Pseudomonas aeruginosa strains isolated from clinical specimens en_US
dc.type Article en_US
dc.identifier.volume 50 en_US
dc.identifier.issue 1 en_US
dc.identifier.startpage 74
dc.identifier.startpage 74 en_US
dc.identifier.endpage 78 en_US
dc.authorid 0000-0001-8764-7701
dc.identifier.doi 10.1111/j.1439-0507.2006.01322.x
dc.relation.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
dc.identifier.pmid 17302753 en_US
dc.identifier.scopus 2-s2.0-33846016929 en_US
dc.identifier.wos WOS:000243306000013 en_US

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